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Report error Found 6 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2' and Ligand = 'BDBM50429899'
TargetCarbonic anhydrase 2(Human)
Vilnius University Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKi:  3.5nMAssay Description:Inhibition of human recombinant CA2 incubated for 15 mins by stop flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Human)
Vilnius University Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant CA2 incubated for 15 mins by stop flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Human)
Vilnius University Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKd:  6.70nMpH: 7.0Assay Description:Binding affinity to human recombinant CA2 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Human)
Vilnius University Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKd: <10nMAssay Description:Inhibition of human carbonic anhydrase 2 at pH7 and 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Human)
Vilnius University Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKd:  6.70nMAssay Description:Inhibition of human carbonic anhydrase 2 at pH7 and 37 degC by fluorescent thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Human)
Vilnius University Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKd: <5nMAssay Description:Inhibition of human carbonic anhydrase 2 at pH7 and 25 degC by stopped-flow kinetic inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed