Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 3' and Ligand = 'BDBM26187'
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26187(α-CA inhibitor, 11 | CHEMBL14060 | US9688816,...)
Affinity DataKi:  2.70E+3nM ΔG°:  -31.8kJ/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26187(α-CA inhibitor, 11 | CHEMBL14060 | US9688816,...)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of human CA3 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26187(α-CA inhibitor, 11 | CHEMBL14060 | US9688816,...)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of human carbonic anhydrase 3 after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26187(α-CA inhibitor, 11 | CHEMBL14060 | US9688816,...)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26187(α-CA inhibitor, 11 | CHEMBL14060 | US9688816,...)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of human carbonic anhydrase 3 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Bos taurus (Cattle))
Ondokuz Mayis University

LigandPNGBDBM26187(α-CA inhibitor, 11 | CHEMBL14060 | US9688816,...)
Affinity DataKi:  4.60E+3nMpH: 7.4Assay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Bos taurus (Cattle))
Ondokuz Mayis University

LigandPNGBDBM26187(α-CA inhibitor, 11 | CHEMBL14060 | US9688816,...)
Affinity DataKi:  4.63E+3nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a spect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Bos taurus (Cattle))
Ondokuz Mayis University

LigandPNGBDBM26187(α-CA inhibitor, 11 | CHEMBL14060 | US9688816,...)
Affinity DataIC50:  4.63E+3nMpH: 7.4Assay Description:The CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed