Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 7' and Ligand = 'BDBM50329832'
TargetCarbonic anhydrase 7(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50329832(5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)
Affinity DataKoff:  1.60E+5s-1Assay Description:Binding affinity to human recombinant CA7 assessed as association rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50329832(5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)
Affinity DataKd:  1.00E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50329832(5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to human recombinant CA7 after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50329832(5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)
Affinity DataKd:  330nMAssay Description:Binding affinity to human recombinant CA7 by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50329832(5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)
Affinity DataKon:  0.270M-1s-1Assay Description:Binding affinity to human recombinant CA7 assessed as dissociation rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50329832(5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 7 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50329832(5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)
Affinity DataKon:  0.270M-1s-1Assay Description:Binding affinity to CA7 (unknown origin) assessed as dissociation rate constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50329832(5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)
Affinity DataKd:  13nMAssay Description:Binding affinity to CA7 (unknown origin) assessed as intrinsic thermodynamic equilibrium constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50329832(5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to recombinant human N-terminal His-tagged carbonic anhydrase 7 (3 to 264 residues) expressed in Escherichia coli BL21 (DE3) in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50329832(5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)
Affinity DataKd:  5.80nMAssay Description:Binding affinity to recombinant human N-terminal His-tagged carbonic anhydrase 7 (3 to 264 residues) expressed in Escherichia coli BL21 (DE3) assesse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed