Found 4 Enz. Inhib. hit(s) with Target = 'Caspase-1' and Ligand = 'BDBM10246' 
Affinity DataKi: 18nM ΔG°: -44.2kJ/molepH: 7.5 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of caspase-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+4nMAssay Description:Amidolytic activity of THP.1 cell lysate against IL-1 beta converting enzyme using C1-Asp-AMC as a substrateChecked by AuthorMore data for this Ligand-Target Pair
