Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Caspase-3' and Ligand = 'BDBM10536'
TargetCaspase-3(Homo sapiens (Human))
Merck Frosst Canada

LigandPNGBDBM10536((3S)-5-(benzylsulfanyl)-3-[(2S)-3-methyl-2-(1-phen...)
Affinity DataIC50:  746nMpH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Merck Frosst Canada

LigandPNGBDBM10536((3S)-5-(benzylsulfanyl)-3-[(2S)-3-methyl-2-(1-phen...)
Affinity DataIC50:  750nMpH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed