Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Caspase-3' and Ligand = 'BDBM36363'
TargetCaspase-3(Homo sapiens (Human))
University of Illinois

LigandPNGBDBM36363(CID6851947 | PAC-1 | US10166229, Example PAC-1)
Affinity DataEC50:  220nMpH: 7.4 T: 2°CAssay Description:Procaspase-3 activation assay; activation of procaspase-3 to caspase-3. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University of Illinois

LigandPNGBDBM36363(CID6851947 | PAC-1 | US10166229, Example PAC-1)
Affinity DataEC50:  220nMAssay Description:Procaspase-3 was recombinantly expressed in E. coli with an N-terminal His-6 tag (SEQ ID NO: 29) and purified. Immunoblotting was performed with an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCaspase-3(Homo sapiens (Human))
University of Illinois

LigandPNGBDBM36363(CID6851947 | PAC-1 | US10166229, Example PAC-1)
Affinity DataEC50:  4.08E+3nMAssay Description:Induction of procaspase 3 activity (unknown origin) using Ac-DEVD-pNa as substrate after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed