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Found 7 Enz. Inhib. hit(s) with Target = 'Caspase-3' and Ligand = 'BDBM50171412'
TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171412(5-(3-Chloro-thiophen-2-yl)-3-(4-trifluoromethyl-ph...)
Affinity DataEC50:  1.21E+3nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 h at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171412(5-(3-Chloro-thiophen-2-yl)-3-(4-trifluoromethyl-ph...)
Affinity DataEC50: >4.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 h at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171412(5-(3-Chloro-thiophen-2-yl)-3-(4-trifluoromethyl-ph...)
Affinity DataEC50:  3.34E+3nMAssay Description:Caspase-3 activation activity tested in ZR75-1 cancer cells done for 24 or 48 h at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171412(5-(3-Chloro-thiophen-2-yl)-3-(4-trifluoromethyl-ph...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in P338 cancer cells done for 24 or 48 h at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171412(5-(3-Chloro-thiophen-2-yl)-3-(4-trifluoromethyl-ph...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in LnCap cancer cells done for 24 or 48 h at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171412(5-(3-Chloro-thiophen-2-yl)-3-(4-trifluoromethyl-ph...)
Affinity DataEC50:  760nMAssay Description:Caspase-3 activation activity tested in HT-29 cancer cells done for 24 or 48 h at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171412(5-(3-Chloro-thiophen-2-yl)-3-(4-trifluoromethyl-ph...)
Affinity DataEC50:  440nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 h at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed