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Found 3 Enz. Inhib. hit(s) with Target = 'Caspase-3' and Ligand = 'BDBM50171417'
TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171417(5-(3-Chloro-thiophen-2-yl)-3-(3-trifluoromethyl-ph...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 h at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171417(5-(3-Chloro-thiophen-2-yl)-3-(3-trifluoromethyl-ph...)
Affinity DataEC50:  900nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 h at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171417(5-(3-Chloro-thiophen-2-yl)-3-(3-trifluoromethyl-ph...)
Affinity DataEC50:  280nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 h at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed