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Enz. Inhib. hit(s) with Target = 'Catechol O-methyltransferase' and Ligand = 'BDBM206349'
Target
Catechol O-methyltransferase
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM206349
(US9260413, Example 8)
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Affinity Data
IC50: 590nM
T: 2°C
Assay Description:
To determine IC50 values in the fluorescence polarization assay, solutions of test compounds were prepared and preincubated with COMT enzyme as state...
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Ligand Info
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