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Found 4 Enz. Inhib. hit(s) with Target = 'Cathepsin K' and Ligand = 'BDBM50095493'
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095493(CHEMBL276169 | N-(1-Cyano-azetidin-3-ylmethyl)-ben...)
Affinity DataKi:  20nMAssay Description:Inhibitory constant of the compound against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095493(CHEMBL276169 | N-(1-Cyano-azetidin-3-ylmethyl)-ben...)
Affinity DataIC50:  17nMAssay Description:Inhibitory constant of the compound against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095493(CHEMBL276169 | N-(1-Cyano-azetidin-3-ylmethyl)-ben...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity tested against Human Cathepsin K using Z-Phe-Arg-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095493(CHEMBL276169 | N-(1-Cyano-azetidin-3-ylmethyl)-ben...)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant human Cathepsin K using Z-Phe-Arg-pNA as substrate preincubated with enzyme for 90 mins followed by substrate addition by f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed