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Found 2 Enz. Inhib. hit(s) with Target = 'Cathepsin S' and Ligand = 'BDBM453318'
TargetCathepsin S(Homo sapiens (Human))
Cortexyme

US Patent
LigandPNGBDBM453318(BDBM553824 | US10730826, Compound 18a)
Affinity DataIC50: >1.00E+4nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of cathepsins B, H, K, L, and S were measured in similar assays. Boc-Leu...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Cortexyme

US Patent
LigandPNGBDBM453318(BDBM553824 | US10730826, Compound 18a)
Affinity DataIC50: >1.00E+4nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent