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Found 2 Enz. Inhib. hit(s) with Target = 'Cathepsin S' and Ligand = 'BDBM50299184'
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50299184(1-(3-(4-chloro-3-((4-chlorophenyl)ethynyl)phenyl)-...)
Affinity DataIC50:  380nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50299184(1-(3-(4-chloro-3-((4-chlorophenyl)ethynyl)phenyl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as invariant chain li degradation by western blottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed