Found 1 Enz. Inhib. hit(s) with Target = 'Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188]' and Ligand = 'BDBM238904' TargetCellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 8.5nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
