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Found 3 Enz. Inhib. hit(s) with Target = 'Cholinesterase' and Ligand = 'BDBM10625'
TargetCholinesterase(Homo sapiens (Human))
Shenyang Pharmaceutical University

LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50:  134nMpH: 8.0Assay Description:The reaction mixture was consisted of 100 µL of the total volume. To the solution of PBS (pH 8.0, 30 µL) consisted of KH2PO4 and K2HPO4 in 96-well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Shenyang Pharmaceutical University

LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50:  733nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Shenyang Pharmaceutical University

LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50:  980nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed