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Found 5 Enz. Inhib. hit(s) with Target = 'Cholinesterase' and Ligand = 'BDBM10949'
TargetCholinesterase(Equus caballus (Horse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM10949(3-(4-{[Benzyl(methyl)amino]methyl}-phenyl)-6,7-dim...)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of equine serum BChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10949(3-(4-{[Benzyl(methyl)amino]methyl}-phenyl)-6,7-dim...)
Affinity DataIC50:  4.89E+4nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10949(3-(4-{[Benzyl(methyl)amino]methyl}-phenyl)-6,7-dim...)
Affinity DataIC50:  4.89E+4nMAssay Description:Inhibition of BuChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10949(3-(4-{[Benzyl(methyl)amino]methyl}-phenyl)-6,7-dim...)
Affinity DataIC50:  4.89E+4nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10949(3-(4-{[Benzyl(methyl)amino]methyl}-phenyl)-6,7-dim...)
Affinity DataIC50:  4.89E+4nMAssay Description:Inhibition of human BuChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed