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Found 11 Enz. Inhib. hit(s) with Target = 'Cholinesterase' and Ligand = 'BDBM50327939'
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataIC50:  8.86E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataIC50:  1.76E+4nMAssay Description:Inhibition of human plasmatic BChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition measured every 2 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataIC50:  1.76E+4nMAssay Description:Inhibition of human plasmatic BuChE assessed as reduction in cholinesterase activity by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataIC50:  1.76E+4nMAssay Description:Inhibition of recombinant human BuChE using butyrylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataIC50:  1.76E+4nMAssay Description:Inhibition of human plasmatic BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of human plasmatic BChE after 5 mins using spectrophotometer by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of human plasmatic BChE after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of human BuChE pre-incubated for 5 mins before butylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of human plasmatic BChE after 5 mins by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum - University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of human plasmatic BChE using butylthiocholne substrate preincubated for 5 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed