Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Co-chaperonin GroES' and Ligand = 'BDBM50495811'
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50495811(CHEMBL3115919)
Show SMILES Cn1c2ccccc2c(O)c(C(=O)Nc2ccncc2)c1=O
Show InChI InChI=1S/C16H13N3O3/c1-19-12-5-3-2-4-11(12)14(20)13(16(19)22)15(21)18-10-6-8-17-9-7-10/h2-9,20H,1H3,(H,17,18,21)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expre...More data for this Ligand-Target Pair
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50495811(CHEMBL3115919)
Show SMILES Cn1c2ccccc2c(O)c(C(=O)Nc2ccncc2)c1=O
Show InChI InChI=1S/C16H13N3O3/c1-19-12-5-3-2-4-11(12)14(20)13(16(19)22)15(21)18-10-6-8-17-9-7-10/h2-9,20H,1H3,(H,17,18,21)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expre...More data for this Ligand-Target Pair
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50495811(CHEMBL3115919)
Show SMILES Cn1c2ccccc2c(O)c(C(=O)Nc2ccncc2)c1=O
Show InChI InChI=1S/C16H13N3O3/c1-19-12-5-3-2-4-11(12)14(20)13(16(19)22)15(21)18-10-6-8-17-9-7-10/h2-9,20H,1H3,(H,17,18,21)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of Escherichia coli GroEL/GroES expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH refolding preinc...More data for this Ligand-Target Pair
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50495811(CHEMBL3115919)
Show SMILES Cn1c2ccccc2c(O)c(C(=O)Nc2ccncc2)c1=O
Show InChI InChI=1S/C16H13N3O3/c1-19-12-5-3-2-4-11(12)14(20)13(16(19)22)15(21)18-10-6-8-17-9-7-10/h2-9,20H,1H3,(H,17,18,21)
Affinity DataIC50: 6.25E+4nMAssay Description:Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expre...More data for this Ligand-Target Pair
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50495811(CHEMBL3115919)
Show SMILES Cn1c2ccccc2c(O)c(C(=O)Nc2ccncc2)c1=O
Show InChI InChI=1S/C16H13N3O3/c1-19-12-5-3-2-4-11(12)14(20)13(16(19)22)15(21)18-10-6-8-17-9-7-10/h2-9,20H,1H3,(H,17,18,21)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expre...More data for this Ligand-Target Pair
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50495811(CHEMBL3115919)
Show SMILES Cn1c2ccccc2c(O)c(C(=O)Nc2ccncc2)c1=O
Show InChI InChI=1S/C16H13N3O3/c1-19-12-5-3-2-4-11(12)14(20)13(16(19)22)15(21)18-10-6-8-17-9-7-10/h2-9,20H,1H3,(H,17,18,21)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of Escherichia coli GroEL/GroES-ATPase activity expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH ...More data for this Ligand-Target Pair
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50495811(CHEMBL3115919)
Show SMILES Cn1c2ccccc2c(O)c(C(=O)Nc2ccncc2)c1=O
Show InChI InChI=1S/C16H13N3O3/c1-19-12-5-3-2-4-11(12)14(20)13(16(19)22)15(21)18-10-6-8-17-9-7-10/h2-9,20H,1H3,(H,17,18,21)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expre...More data for this Ligand-Target Pair