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Found 2 Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM12566'
TargetCoagulation factor X(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM12566(6-chloro-N-methyl-N-[(3S)-1-[(2S)-1-(morpholin-4-y...)
Affinity DataKi:  10nM ΔG°:  -45.7kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM12566(6-chloro-N-methyl-N-[(3S)-1-[(2S)-1-(morpholin-4-y...)
Affinity DataIC50:  70nMAssay Description:D3R245More data for this Ligand-Target Pair
In DepthDetails PubMed