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Found 2 Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM304117'
TargetCoagulation factor XI(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM304117((S)- or (R)-2-(1-((4- carboxyphenyl)amino)-3-cyclo...)
Affinity DataIC50:  2.80nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM304117((S)- or (R)-2-(1-((4- carboxyphenyl)amino)-3-cyclo...)
Affinity DataIC50: >1.00E+3nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent