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Found 2 Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM304228'
TargetCoagulation factor XI(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM304228(2-(1-((4-carboxy-3- fluorophenyl)amino)-3- cyclobu...)
Affinity DataIC50:  0.100nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM304228(2-(1-((4-carboxy-3- fluorophenyl)amino)-3- cyclobu...)
Affinity DataIC50:  80.3nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent