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Found 3 Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM50063581'
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50063581(CHEMBL3398612)
Affinity DataKi:  0.310nMAssay Description:Inhibition of human coagulation factor 11a at 25 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50063581(CHEMBL3398612)
Affinity DataKi:  0.310nMAssay Description:Competitive inhibition of human coagulation factor 11a assessed as reduction in release of p-nitroaniline after 10 to 120 mins by Michaelis-Menten eq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50063581(CHEMBL3398612)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to coagulation factor 11a (unknown origin) assessed as inhibition constant using (p-Glu-Pro-Arg-pNa,HCl) as substrate preincubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed