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Found 4 Enz. Inhib. hit(s) with Target = 'Complement C1r subcomponent' and Ligand = 'BDBM50063745'
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063745(2-(2-Iodo-phenylamino)-7-trifluoromethyl-benzo[d][...)
Affinity DataIC50:  400nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063745(2-(2-Iodo-phenylamino)-7-trifluoromethyl-benzo[d][...)
Affinity DataIC50:  400nMAssay Description:Compound was evaluated in vitro for inhibitory activity against purified human C1r protease proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063745(2-(2-Iodo-phenylamino)-7-trifluoromethyl-benzo[d][...)
Affinity DataIC50:  4.00E+3nMAssay Description:Evaluated in vitro for inhibitory activity against purified human C1r protease incubated in buffer for 60 minutesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063745(2-(2-Iodo-phenylamino)-7-trifluoromethyl-benzo[d][...)
Affinity DataIC50:  4.00E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed