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Found 2 Enz. Inhib. hit(s) with Target = 'Complement factor B' and Ligand = 'BDBM50314024'
TargetComplement factor B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50314024((6S,9S,12S,15S,18S,21S)-21-acetamido-1,26-diamino-...)
Affinity DataIC50:  600nMpH: 9.5Assay Description:Inhibition of human complement factor B treated for 5 mins before addition of substrate Ac-SHLGLAR-pNA at pH 9.5 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement factor B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50314024((6S,9S,12S,15S,18S,21S)-21-acetamido-1,26-diamino-...)
Affinity DataIC50:  5.00E+4nMpH: 7.4Assay Description:Inhibition of human C3 convertase assessed as inhibition of C3a and C3b fragment production at pH 7.4 after 30 mins by SDS-PAGEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed