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Found 3 Enz. Inhib. hit(s) with Target = 'Complement factor D' and Ligand = 'BDBM171332'
TargetComplement factor D(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM171332(US9085555, 762)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compound at vario...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetComplement factor D(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM171332(US9085555, 762)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human complement factor D catalytic domain using Z-Lys-thiobenzylester as substrate preincubated for 1 hr followed by subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement factor D(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM171332(US9085555, 762)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human complement factor D catalytic domain using Z-Lys-thiobenzylester as substrate preincubated for 1 hr followed by subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed