Affinity DataIC50: 32nMAssay Description:Competitive inhibition of human complement factor D preincubated for 1 hr followed by addition of Z-Lys-thiobenzyl ester as substrate measured over 5...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of human serum factor D-mediated complement activation in rabbit erythrocytes assessed as reduction in rabbit erythrocyte hemolysis preinc...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of CFD in 50% human whole blood assessed as reduction in alternate complement pathway-mediated MAC formation pre-incubated for 15 mins fol...More data for this Ligand-Target Pair
Affinity DataKd: 17nMAssay Description:Binding affinity to recombinant human C-terminal 6His-tagged/biotinylated complement factor D (26 to 253 residues) expressed in Sf9 insect cells by b...More data for this Ligand-Target Pair