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Found 3 Enz. Inhib. hit(s) with Target = 'Complement factor D' and Ligand = 'BDBM50201568'
TargetComplement factor D(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50201568(CHEMBL3951127)
Affinity DataIC50:  19nMAssay Description:Inhibition of human serum factor D-mediated complement activation in rabbit erythrocytes assessed as reduction in rabbit erythrocyte hemolysis preinc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement factor D(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50201568(CHEMBL3951127)
Affinity DataIC50:  6.60E+3nMAssay Description:Competitive inhibition of human complement factor D preincubated for 1 hr followed by addition of Z-Lys-thiobenzyl ester as substrate measured over 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement factor D(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50201568(CHEMBL3951127)
Affinity DataKd:  1.20E+4nMAssay Description:Binding affinity to recombinant human C-terminal 6His-tagged/biotinylated complement factor D (26 to 253 residues) expressed in Sf9 insect cells by b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed