Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50223025'
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50223025(CHEMBL249212 | N2-(3,5-dichloropyridin-2-yl)-3,6-d...)
Show SMILES CCc1nc(N(C)c2ncc(Cl)cc2Cl)c(CC)nc1N[C@H]1[C@H](Cc2ccccc12)OCCF
Show InChI InChI=1S/C25H28Cl2FN5O/c1-4-19-23(32-22-17-9-7-6-8-15(17)12-21(22)34-11-10-28)30-20(5-2)25(31-19)33(3)24-18(27)13-16(26)14-29-24/h6-9,13-14,21-22H,4-5,10-12H2,1-3H3,(H,30,32)/t21-,22+/m0/s1
Affinity DataKi:  1.21E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from CRF1 receptor in IMR32 cellsMore data for this Ligand-Target Pair