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Found 2 Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50272638'
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50272638(2-(4-chloro-2,6-dimethoxyphenyl)-4-methoxy-6-methy...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50272638(2-(4-chloro-2,6-dimethoxyphenyl)-4-methoxy-6-methy...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at CRF1 receptor expressed in mouse AtT20 cells assessed as inhibition of sauvagine-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed