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Found 3 Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 2' and Ligand = 'BDBM50153473'
TargetCorticotropin-releasing factor receptor 2(Mus musculus)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50153473(CHEMBL3775796)
Affinity DataKi:  0.360nMAssay Description:Displacement of [125ITyr0-Glu1]-PD-Svg in mouse CRF-R2 beta expressed in COS-M6 cells after 90 mins by gamma counting assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 2(Mus musculus)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50153473(CHEMBL3775796)
Affinity DataKi:  0.940nMAssay Description:Displacement of [125ITyr0-Glu1,Nle17]-PS-Svg in mouse CRF-R2 beta expressed in COS-M6 cells after 90 mins by gamma counting assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 2(RAT)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50153473(CHEMBL3775796)
Affinity DataEC50:  1nMAssay Description:Antagonist activity at CRF-R2 beta in rat A7r5 cells assessed as inhibition of rat Ucn1 induced cAMP accumulation after 30 mins by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed