Found 3 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 4/G1/S-specific cyclin-D1' and Ligand = 'BDBM50193086' TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human N-terminal GST-tagged CDK4/cyclin D1 expressed in baculovirus infected Sf9 insect cells using retinoblastoma (792 to 928 residues...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human CDK4/cyclin D1 expressed in baculovirus expression system after 30 mins in presence of [gamma-33P]ATP by scintillation counting a...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATP by filter binding assayMore data for this Ligand-Target Pair
