Found 2 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 4/G1/S-specific cyclin-D1' and Ligand = 'BDBM6683' TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
University Of South Australia Cancer Research Institute
Curated by ChEMBL
University Of South Australia Cancer Research Institute
Curated by ChEMBL
Affinity DataIC50: 786nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin) using pRb (246 to 257 residues) as substrate in presence of [gamma33P]-ATP by topcount scintillation co...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
University Of South Australia Cancer Research Institute
Curated by ChEMBL
University Of South Australia Cancer Research Institute
Curated by ChEMBL
Affinity DataIC50: 786nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
