Compile Data Set for Download or QSAR
maximum 50k data
Found 1 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C]' and Ligand = 'BDBM14189'
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM14189(7-cyclohexyl-N-[4-(4-methylpiperazin-1-yl)phenyl]-...)
Affinity DataIC50:  31nMAssay Description:The compounds were tested for their ability to inhibit the phosphorylation of serine 795 of Rb by purified recombinant CDK4. The phosphorylation of s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed