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Found
1
Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 4' and Ligand = 'BDBM147049'
Target
Cyclin-dependent kinase 4
(Homo sapiens (Human))
Novartis
US Patent
Ligand
BDBM147049
(US8957074, 89)
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Affinity Data
IC50: 3nM
pH: 7.5 T: 2°C
Assay Description:
An assay for monitoring CDK4/cyclin D1-catalyzed phosphorylation of pRb at the Ser780 site was performed using TR-FRET in a 384-well format, and was ...
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Ligand Info
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