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Found
1
Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 4' and Ligand = 'BDBM525763'
Target
Cyclin-dependent kinase 4
(Homo sapiens (Human))
Nuvation Bio
US Patent
Ligand
BDBM525763
(US11174252, Compound 450)
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Affinity Data
IC50: 0.5nM
Assay Description:
CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...
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Target Info
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NCI pathway
Reactome pathway
KEGG
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Ligand Info
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Details
US Patent
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