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Found 2 Enz. Inhib. hit(s) with Target = 'Cystic fibrosis transmembrane conductance regulator [1-507,509-1480]' and Ligand = 'BDBM526498'
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM526498(US11186566, Compound 37)
Affinity DataEC50:  70nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM526498(US11186566, Compound 37)
Affinity DataEC50: <100nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent