Affinity DataIC50: 540nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 890nMAssay Description:Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins using ATRA and NADPH by HPLC methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP26A1 in human MCF7 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 7.00E+3nMAssay Description:The imidazole derivatives were evaluated for their retinoic acid metabolism inhibitory activity using a MCF-7 cell assay, using radiolabelled all-tra...More data for this Ligand-Target Pair