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Found 2 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 26B1' and Ligand = 'BDBM50253810'
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50253810(CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4-triazol-1...)
Affinity DataIC50:  0.460nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50253810(CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4-triazol-1...)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed