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Found 4 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 2D6' and Ligand = 'BDBM50366613'
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50366613(DEXTROMETHORPHAN)
Affinity DataIC50:  41nMAssay Description:Inhibition of CYP2D6 in human liver microsomes incubated for 15 to 40 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50366613(DEXTROMETHORPHAN)
Affinity DataIC50:  43nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50366613(DEXTROMETHORPHAN)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of MAMC O-dealkylation mediated by human Cytochrome P450 2D6 expressed in human lymphoblastoid cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50366613(DEXTROMETHORPHAN)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human CYP2D6 expressed in Escherichia coli JM109More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed