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Found 2 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 3A4' and Ligand = 'BDBM143362'
TargetCytochrome P450 3A4(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM143362(US9682953, 20.A-5)
Affinity DataIC50: >13nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate preincubated for 5 mins followed by NADPH cofactor addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM143362(US9682953, 20.A-5)
Affinity DataIC50: >13nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins followed by NADPH cofactor addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed