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Found 5 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 3A4' and Ligand = 'BDBM50275147'
TargetCytochrome P450 3A4(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50275147(6-Gingerol | BDBM50317427 | CHEMBL446043 | Gingero...)
Affinity DataIC50:  2.18E+4nMAssay Description:Inhibition of recombinant human CYP3A4 expressed in baculosomes using Vivid BOMCC substrate blue measured every 30 sec for 30 mins by fluorescence as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50275147(6-Gingerol | BDBM50317427 | CHEMBL446043 | Gingero...)
Affinity DataIC50:  3.20E+4nMAssay Description:In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC4R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50275147(6-Gingerol | BDBM50317427 | CHEMBL446043 | Gingero...)
Affinity DataIC50:  3.74E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate preincubated for 10 mins followed by NADPH addition measured after 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50275147(6-Gingerol | BDBM50317427 | CHEMBL446043 | Gingero...)
Affinity DataIC50:  4.29E+4nMAssay Description:Inhibition of recombinant human CYP3A4 expressed in baculosomes using Vivid BOMR substrate red measured every 30 sec for 30 mins by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50275147(6-Gingerol | BDBM50317427 | CHEMBL446043 | Gingero...)
Affinity DataIC50:  7.34E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed