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Found 3 Enz. Inhib. hit(s) with Target = 'Cytochrome c oxidase subunit 1' and Ligand = 'BDBM11639'
TargetCytochrome c oxidase subunit 1(Ovis aries)
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of ovine COX1 preincubated for 5 mins followed by arachidonic acid addition and measured after 2 mins by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 1(Ovis aries)
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  2.43E+4nMAssay Description:Inhibition of sheep COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 1(Ovis aries)
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  2.73E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha incubated for 2 mins using arachidonic acid as substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed