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Found 7 Enz. Inhib. hit(s) with Target = 'Cytochrome c oxidase subunit 2' and Ligand = 'BDBM11639'
TargetCytochrome c oxidase subunit 2(Ovis aries)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  43nMAssay Description:Inhibition of ovine COX-2 colorimetric enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  60nMAssay Description:Inhibition of sheep COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  90nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid as substrate measured after 2 mins by colorimetric enzyme immune assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  160nMAssay Description:Inhibition of ovine COX-2 by colorimetric inhibitor screening assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  280nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  293nMAssay Description:Inhibition of recombinant human COX2 assessed as reduction in PGF2alpha incubated for 2 mins using arachidonic acid as substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  540nMAssay Description:Thromboxane (TXA2) receptor antagonist activity using human plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed