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Found 5 Enz. Inhib. hit(s) with Target = 'Cytoplasmic tyrosine-protein kinase BMX' and Ligand = 'BDBM250082'
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM250082(US9447106, 27b (peak 2) | US9556188, Compound 27a)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of human BMX using poly[Glu:Tyr] (4:1) as substrate preincubated for 60 mins followed by [gamma-33P]-ATP addition and measured after 120 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM250082(US9447106, 27b (peak 2) | US9556188, Compound 27a)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of human BMX using poly[Glu:Tyr] (4:1) as substrate preincubated for 60 mins followed by [gamma-33P]-ATP addition and measured after 120 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM250082(US9447106, 27b (peak 2) | US9556188, Compound 27a)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of full-length N-terminal GST-tagged BMX (1 to 675 residues) (unknown origin) expressed in Sf21 insect cells using NH2-ETVYSEVRK-biotin as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM250082(US9447106, 27b (peak 2) | US9556188, Compound 27a)
Affinity DataIC50:  12nMAssay Description:Inhibition of N-terminal GST-tagged BMX (1 to 675 residues) (unknown origin) expressed in Sf21 insect cells using NH2-ETVYSEVRK-biotin as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM250082(US9447106, 27b (peak 2) | US9556188, Compound 27a)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to BMX (unknown origin) assessed as dissociation constant by KINOMEscan analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed