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Found 4 Enz. Inhib. hit(s) with Target = 'D(1A) dopamine receptor' and Ligand = 'BDBM435739'
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM435739(2-(2,6-dichlorophenyl)-1-((1S,3R)-3-(hydroxymethyl...)
Affinity DataEC50:  16.4nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM435739(2-(2,6-dichlorophenyl)-1-((1S,3R)-3-(hydroxymethyl...)
Affinity DataEC50:  151nMAssay Description:Positive allosteric modulation of mouse D1 receptor expressed in HEK293 cells assessed as increase in cyclic AMP production measured after 60 mins in...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM435739(2-(2,6-dichlorophenyl)-1-((1S,3R)-3-(hydroxymethyl...)
Affinity DataEC50:  12nMAssay Description:Positive allosteric modulation of human D1 receptor in HEK293 cells assessed as increase in cyclic AMP production measured after 60 mins in presence ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM435739(2-(2,6-dichlorophenyl)-1-((1S,3R)-3-(hydroxymethyl...)
Affinity DataEC50:  16nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed