Affinity DataKi: 0.537nMAssay Description:In vitro ability to displace [3H]spiperone binding from dopamine receptor D2 in rat striatal membrane.More data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Inhibitory constant against binding of [125I]- IBZM to rat striatal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 648nMAssay Description:In vitro affinity of compound towards Dopamine receptor D2 was determined by measuring their ability to displace [3H]-spiperone from rat striatal hom...More data for this Ligand-Target Pair
Affinity DataKi: 760nMAssay Description:Binding affinity towards Dopamine receptor D2 in rat striatal tissue by [3H]-spiperone displacement.More data for this Ligand-Target Pair
Affinity DataKi: 820nMAssay Description:In vivo compound was evaluated for binding towards Dopamine receptor D2 in rat striatal membranes using competitive binding assay and [125I]IBZM radi...More data for this Ligand-Target Pair
Affinity DataKi: 886nMAssay Description:Binding affinity for dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 891nMAssay Description:In vitro inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataKi: 900nMAssay Description:Inhibition of [3H]spiperone binding to Dopamine receptor D2 at 0.02 nMMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity at Dopamine receptor D2 in rat striatal homogenate by [3H]-spiperone displacement.More data for this Ligand-Target Pair
Affinity DataKi: 1.21E+3nMAssay Description:Compound was evaluated for affinity towards dopamine D2-like receptor in homogenate of caudate putamen tissue from rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Antagonist activity at human D2 receptor expressed in CHO-K1 cells assessed as inhibition of dopamine-induced calcium flux incubated for 60 mins at 3...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Antagonist activity at dopamine D2 receptor long isoform (unknown origin) expressed in HEK293 cells assessed as inhibition of dopamine-induced calciu...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of 0.1 nM of [125I]- (S)-N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide binding in striatal homogenates of rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of [3H](S)-sulpiride binding in striatal homogenates of rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 2.05E+3nMAssay Description:Antagonist activity at D2 receptor (unknown origin) expressed in CHOK1 cells assessed as inhibition of dopamine-induced calcium flux preincubated for...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro binding affinity towards rat Dopamine receptor D2 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]- -spiperone from Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair