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Found 4 Enz. Inhib. hit(s) with Target = 'D(3) dopamine receptor' and Ligand = 'BDBM50274355'
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274355(CHEMBL484358 | N-[N'-(4-Ethynylcyclohex-3-en-1-yl)...)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274355(CHEMBL484358 | N-[N'-(4-Ethynylcyclohex-3-en-1-yl)...)
Affinity DataKi:  0.780nMAssay Description:Displacement of [3H]spiperone from human wild type D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274355(CHEMBL484358 | N-[N'-(4-Ethynylcyclohex-3-en-1-yl)...)
Affinity DataEC50:  2.10nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells assessed as inhibition of forskolin-induced cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274355(CHEMBL484358 | N-[N'-(4-Ethynylcyclohex-3-en-1-yl)...)
Affinity DataEC50:  1.60nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells by [3H]thymidine incorporation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed