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Found 1 Enz. Inhib. hit(s) with Target = 'DNA ligase 1' and Ligand = 'BDBM23040'
TargetDNA ligase 1(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM23040(7-(4-methoxyphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol...)
Affinity DataKi:  6.20nM ΔG°:  -46.4kJ/mole IC50:  20nMpH: 9.0 T: 2°CAssay Description:The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed