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Found 5 Enz. Inhib. hit(s) with Target = 'DNA polymerase beta' and Ligand = 'BDBM23208'
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM23208((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM23208((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of rat DNA polymerase beta in presence of 0.1 mg/mL BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM23208((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,...)
Affinity DataIC50:  3.37E+4nMAssay Description:Inhibition of lyase activity of DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM23208((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,...)
Affinity DataIC50:  4.36E+4nMAssay Description:Inhibition of DNA polymerase beta lyase activity by deoxyribose phosphate excision assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM23208((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,...)
Affinity DataIC50:  4.63E+4nMAssay Description:Inhibition of polymerase activity of DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed