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Found 3 Enz. Inhib. hit(s) with Target = 'DNA polymerase beta' and Ligand = 'BDBM50448689'
TargetDNA polymerase beta(Rattus norvegicus)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50448689(CHEMBL3127730)
Affinity DataKi:  5.50E+3nMAssay Description:Competitive inhibition of recombinant rat DNA polymerase beta using poly(dA)/oligo(dT)18 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50448689(CHEMBL3127730)
Affinity DataKi:  1.16E+4nMAssay Description:Noncompetitive inhibition of recombinant rat DNA polymerase beta using dTTP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50448689(CHEMBL3127730)
Affinity DataIC50:  3.56E+4nMAssay Description:Inhibition of recombinant rat DNA polymerase beta expressed in Escherichia coli JMpbeta5 assessed as inhibition of incorporation of dTTP into poly(dA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed