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Found 2 Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 1' and Ligand = 'BDBM50034014'
TargetDNA topoisomerase 1(Homo sapiens (Human))
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50034014((S)-4-Ethyl-4-hydroxy-11-methyl-3,13-dioxo-3,4,12,...)
Affinity DataIC50:  143nMAssay Description:Inhibitory activity against DNA topoisomerase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50034014((S)-4-Ethyl-4-hydroxy-11-methyl-3,13-dioxo-3,4,12,...)
Affinity DataIC50:  143nMAssay Description:In vitro fragmentation of DNA in the presence of excess calf thymus topoisomerase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed